Nonsedating anxiolytic

Classical anxiolytics (diazepam and meprobamate) and proposed anxiolytic drugs having low sedative potential (CL 218,872 and tracazolate) generalized to the CGS 9896 discriminative cue.

The CGS 9896 cue appeared to be mediated by a pure anxiolytic action as previous research has shown that this compound does not produce sedation or muscle relaxation.

However, nonbenzodiazepines have dissimilar or entirely different chemical structures and are therefore unrelated to benzodiazepines on a molecular level.

The nonbenzodiazepines are positive allosteric modulators of the GABA-A receptor.

Anxiolytic medications have been used for the treatment of anxiety disorder and its related psychological and physical symptoms.

Last modified 28-Dec-2019 16:45